13 September 2014

# 28.1 The mitotic cell cycle - Syllabus 2015

• Replication and division of nuclei and cells
• Understanding of chromosome behaviour in mitosis

Learning Outcomes

Candidates should be able to:

(a) explain the importance of mitosis in the production of genetically identical cells, growth, repair and asexual reproduction;

(b) outline the cell cycle, including growth, DNA replication, mitosis and cytokinesis;

(c) [PA] describe, with the aid of diagrams, the behaviour of chromosomes during the mitotic cell cycle and the associated behaviour of the nuclear envelope, cell membrane, centrioles and spindle (names of the main stages are expected);

(d) explain how uncontrolled cell division can result in the formation of a tumour and identify factors that can increase the chances of cancerous growth;

(e) explain the meanings of the terms haploid and diploid (see section 5) and the need for a reduction
division (meiosis) prior to fertilisation in sexual reproduction (note: descriptions of homologous
chromosomes are not required for AS Level);

(f) use the knowledge gained in this section in new situations or to solve related problems.

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